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Table 1 Average computation time (in minutes) over 5 replicates for varying dimensions of \(\tilde{\mathbf {X}}^{ G }\), with the dimension of \(\tilde{\mathbf {X}}^{ G }\) being fixed (\(N_{ M }=6\))

From: Fast computation of genome-metagenome interaction effects

\(N_{ G }\) 50 100 500 1000 1500 2000 3000 4000
\(\rho \)-SICOMORE 0.01 0.01 0.02 0.03 0.03 0.04 0.05 0.06
SICOMORE 0.21 0.34 0.82 0.76 0.75 0.96 0.93 1.09
MLGL 0.06 0.09 3.35 0.86 3.12 4.52 8.02 24.20
GLtree 0.07 0.28 0.67 3.83 11.69 26.31 88.17 210.64
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