Fig. 11

Copy number spectrum plot generated by Merqury as k-mers (\(k=21\) as recommended) plotted as stacked histograms colored by the copy numbers found in the 10\(\times \) long-read coverage assembly of LazyB. The typical peak generated at slightly less than twice the short-read coverage (\(2\cdot 43\times = 86\times \)) in concordance with the absence of higher copy numbers clearly indicate the presence of only a single mixed haplotype. The small elevation of k-mers only found in reads at the level short-read coverage can be attributed to few haplotype regions not fitting well to the mixture. The slight shift in short-read coverage versus k-mers arises out of the uncorrected high error rate of long reads