Fig. 6

PACTION results for patient A12. a The SNV clone tree reported by Gundem et al. [23] where the authors manually annotated edges with CNA events. b SNV clone tree \(T_1\) and CNA clone tree \(T_2\) describing the evolution of the SNV clones \(\Pi _1\) and CNA clones \(\Pi _2\) in the tumor samples of patient A12, respectively. c Proportions \(U_1\) of SNV clones \(\Pi _1\) and proportions \(U_2\) of CNA clones \(\Pi _2\) in the four samples of patient A12. d Proportions U of tumor clones \(\Pi\) in the four samples of patient A12 inferred by PACTION. e Integrated clone tree T inferred by PACTION. amp: amplification, del: deletion, LOH: loss of heterozygosity