A classification algorithm based on dynamic ensemble selection to predict mutational patterns of the envelope protein in HIV-infected patients

Table 3 Prediction of variability in the high-mannose patch of Env by KBC and other algorithms

Clade	Method	Balanced Accuracy ^a,b	Accuracy	Precision	Recall	F1 Score
Clade C	KBC	0.65 (± 0.05)	0.69 (± 0.05)	0.67 (± 0.08)	0.47 (± 0.05)	0.55 (± 0.08)
	DT	0.59 (± 0.05)	0.63 (± 0.07)	0.54 (± 0.07)	0.39 (± 0.21)	0.43 (± 0.17)
	RF	0.59 (± 0.02)	0.63 (± 0.03)	0.60 (± 0.05)	0.34 (± 0.13)	0.42 (± 0.10)
	QDA	0.60 (± 0.02)	0.63 (± 0.04)	0.57 (± 0.02)	0.39 (± 0.16)	0.45 (± 0.12)
	LDA	0.58 (± 0.04)	0.62 (± 0.06)	0.54 (± 0.07)	0.39 (± 0.17)	0.44 (± 0.13)
	NB	0.61 (± 0.06)	0.63 (± 0.08)	0.54 (± 0.08)	0.52 (± 0.21)	0.52 (± 0.14)
	ADA	0.50 (± 0.05)	0.44 (± 0.04)	0.42 (± 0.02)	0.88 (± 0.09)	0.56 (± 0.02)
	LogReg	0.57 (± 0.06)	0.61 (± 0.04)	0.55 (± 0.07)	0.33 (± 0.20)	0.38 (± 0.15)
	SVM	0.58 (± 0.04)	0.62 (± 0.06)	0.56 (± 0.06)	0.35 (± 0.23)	0.40 (± 0.17)
Clade B	KBC	0.65 (± 0.02)	0.74 (± 0.02)	0.68 (± 0.06)	0.39 (± 0.03)	0.50 (± 0.04)
	DT	0.60 (± 0.05)	0.70 (± 0.02)	0.61 (± 0.03)	0.29 (± 0.16)	0.36 (± 0.16)
	RF	0.62 (± 0.00)	0.72 (± 0.00)	0.61 (± 0.02)	0.35 (± 0.02)	0.45 (± 0.01)
	QDA	0.63 (± 0.01)	0.73 (± 0.01)	0.64 (± 0.03)	0.36 (± 0.02)	0.46 (± 0.02)
	LDA	0.64 (± 0.01)	0.72 (± 0.01)	0.61 (± 0.01)	0.40 (± 0.04)	0.48 (± 0.03)
	NB	0.67 (± 0.04)	0.70 (± 0.03)	0.53 (± 0.05)	0.59 (± 0.07)	0.56 (± 0.06)
	ADA	0.41 (± 0.05)	0.29 (± 0.02)	0.28 (± 0.03)	0.74 (± 0.14)	0.40 (± 0.05)
	LogReg	0.64 (± 0.02)	0.72 (± 0.01)	0.61 (± 0.02)	0.39 (± 0.05)	0.47 (± 0.03)
	SVM	0.63 (± 0.02)	0.70 (± 0.02)	0.55 (± 0.03)	0.41 (± 0.01)	0.47 (± 0.02)

^aStandard deviation values are indicated in parentheses
^bValues in bold font indicate the highest point estimation value for each metric

ISSN: 1748-7188