Advertisement
Page 8 of 8
An important challenge in eukaryotic gene prediction is accurate identification of alternatively spliced exons. Functional transcripts can go undetected in gene expression studies when alternative splicing onl...
Citation: Algorithms for Molecular Biology 2006 1:14
Discovering approximately repeated patterns, or motifs, in biological sequences is an important and widely-studied problem in computational molecular biology. Most frequently, motif finding applications arise ...
Citation: Algorithms for Molecular Biology 2006 1:13
The String Barcoding (SBC) problem, introduced by Rash and Gusfield (RECOMB, 2002), consists in finding a minimum set of substrings that can be used to distinguish between all members of a set of given strings...
Citation: Algorithms for Molecular Biology 2006 1:12
Bifurcation analysis has proven to be a powerful method for understanding the qualitative behavior of gene regulatory networks. In addition to the more traditional forward problem of determining the mapping from ...
Citation: Algorithms for Molecular Biology 2006 1:11
Two important and not yet solved problems in bacterial genome research are the identification of horizontally transferred genes and the prediction of gene expression levels. Both problems can be addressed by m...
Citation: Algorithms for Molecular Biology 2006 1:10
Given a set S of n locally aligned sequences, it is a needed prerequisite to partition it into groups of very similar sequences to facilitate subsequent computations, such as the generation of a phylogenetic tree...
Citation: Algorithms for Molecular Biology 2006 1:9
Recently, we performed an assessment of 13 popular computational tools for discovery of transcription factor binding sites (M. Tompa, N. Li, et al., "Assessing Computational Tools for the Discovery of Transcri...
Citation: Algorithms for Molecular Biology 2006 1:8
Most cellular processes are carried out by multi-protein complexes, groups of proteins that bind together to perform a specific task. Some proteins form stable complexes, while other proteins form transient as...
Citation: Algorithms for Molecular Biology 2006 1:7
Automated software tools for multiple alignment often fail to produce biologically meaningful results. In such situations, expert knowledge can help to improve the quality of alignments.
Citation: Algorithms for Molecular Biology 2006 1:6
The technique of Finite Markov Chain Imbedding (FMCI) is a classical approach to complex combinatorial problems related to sequences. In order to get efficient algorithms, it is known that such approaches need...
Citation: Algorithms for Molecular Biology 2006 1:5
Motif patterns of maximal saturation emerged originally in contexts of pattern discovery in biomolecular sequences and have recently proven a valuable notion also in the design of data compression schemes. Inf...
Citation: Algorithms for Molecular Biology 2006 1:4
RNA has been recognized as a key player in cellular regulation in recent years. In many cases, non-coding RNAs exert their function by binding to other nucleic acids, as in the case of microRNAs and snoRNAs. T...
Citation: Algorithms for Molecular Biology 2006 1:3
The genomes of many species are dominated by short sequences repeated consecutively. It is estimated that over 10% of the human genome consists of tandemly repeated sequences. Finding repeated regions in long ...
Citation: Algorithms for Molecular Biology 2006 1:2
This editorial announces Algorithms for Molecular Biology, a new online open access journal published by BioMed Central. By launching the first open access journal on algorithmic bioinformatics, we provide a foru...
Citation: Algorithms for Molecular Biology 2006 1:1
Advertisement
Algorithms for Molecular Biology
